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Jiangsu Hengrui Pharmaceuticals Co., Ltd. Jiangsu Hengrui Pharmaceutical Co., Ltd.

(a joint stock limited company incorporated in the People's Republic of China) (Stock code: 1276)

Overseas regulatory announcement

This announcement is made in accordance with Rule 13.10B of the Rules Governing the Listing of Securities on The Stock Exchange of Hong Kong Limited.

In accordance with the relevant laws and regulations of the People's Republic of China, Jiangsu Hengrui Pharmaceutical Co., Ltd. (the "Company")

The Shanghai Stock Exchange website (www.sse.com.cn) published the following announcement. They are listed below for reference only.

By order of the board of directors Jiangsu Hengrui Pharmaceutical Co., Ltd. Chairman

Mr. Sun Piaoyang

Shanghai, China March 25, 2026

As at the date of this announcement, members of the Board of Directors include (i) Executive Directors Mr. Sun Piaoyang, Mr. Dai Hongbin, and Mr. Feng Jinu; Mr. Zhang Lianshan, Mr. Jiang Ningjun and Mr. Sun Jieping; (ii) Ms. Guo Congzhao, a non-executive director; and (iii)

Independent non-executive directors are Mr. Dong Jiahong, Mr. Zeng Qingsheng, Mr. Sun Jinyun and Mr. Zhou Ji'en.

Securities code: 600276 Securities abbreviation: Hengrui Medicine Announcement number: 2026-052

Jiangsu Hengrui Pharmaceutical Co., Ltd.

Notice on Convening the 2025 Annual Shareholders Meeting

The board of directors and all directors of the company guarantee that the contents of this announcement do not contain any false records or misleading statements.

or major omissions, and assume legal responsibility for the authenticity, accuracy and completeness of its content.

Important content reminder:

 Date of shareholders’ meeting: April 16, 2026  The online voting system adopted for this shareholders’ meeting: Shanghai Stock Exchange Shareholders’ Meeting Online Voting System

1. Basic information on convening the meeting

(1) Type and session of shareholders’ meeting

2025 Annual Shareholders Meeting

(2) Convener of shareholders’ meeting: Board of Directors (3) Voting method: The voting method used in this shareholders’ meeting is a combination of on-site voting and online voting.

way

(4) Date, time and place of on-site meeting

Date and time of the meeting: April 16, 2026 14:30 Venue: Company Conference Room (No. 1288 Haike Road, Pudong New District, Shanghai)

(5) Online voting system, start and end dates and voting time.

Online voting system: Shanghai Stock Exchange Shareholders Meeting online voting system

Online voting starts and ends on April 16, 2026

Until April 16, 2026 Adopting the Shanghai Stock Exchange online voting system, the voting time of the voting platform through the trading system is

The trading time period on the day when the Eastern Conference is held, namely 9:15-9:25, 9:30-11:30, 13:00-15:00; passed

The voting time of the Internet voting platform is 9:15-15:00 on the day of the shareholders' meeting.

(6) Voting procedures for margin trading, securities lending, refinancing, agreed repurchase business accounts and Shanghai-Hong Kong Stock Connect investors

Involving accounts related to margin trading and securities lending, refinancing business, agreed repurchase business, and Shanghai-Hong Kong Stock Connect investors Voting shall be carried out in accordance with the "Shanghai Stock Exchange Self-Regulatory Guidelines for Listed Companies No. 1 - Standardized Operations"

"Work" and other relevant regulations shall be implemented.

(7) Involving public solicitation of shareholder voting rights

Not applicable

2. Matters to be considered at the meeting The resolutions to be reviewed and the types of voting shareholders at this shareholders’ meeting

Voting shareholder type Serial number Bill name A share shareholders H share shareholders

Non-cumulative voting motion 1 The company’s 2025 board of directors work report √ √ 2 The company’s 2025 annual report √ √ The company’s 2025 profit distribution plan and submission to the shareholders’ meeting for authorization 3 √ √ The board of directors’ proposal to formulate the mid-term dividend plan for 2026 4 Proposal on Re-appointment of Accounting Firm √ √ Regarding the implementation of remuneration for the company’s directors and senior managers in 2025 5 √ √ case motion 6 Proposal on purchasing liability insurance for directors and senior managers √ √ Regarding the general proposal for the shareholders' meeting to authorize the board of directors to issue additional shares of the company 7 √ √ motion to authorize 8.00 Proposal on formulating and revising some of the company’s governance systems √ √ 8.01 Proposal on amending the "Rules of Procedure for Shareholders' Meetings" √ √ 8.02 Proposal on amending the "Rules of Procedures of the Board of Directors" √ √ Regarding the formulation of the "Remuneration Management System for Directors and Senior Management Personnel" 8.03 √ √ motion 9 Proposal on the remuneration plan for directors and senior management √ √ 10.00 Proposal on the election of non-independent directors of the 10th Board of Directors √ √ 10.01 Sun Piaoyang √ √ 10.02 Dai Hongbin √ √ 10.03 Feng Ji √ √ 10.04 Zhang Lianshan √ √

10.05 Jiang Ningjun √ √ 10.06 Guo Congzhao √ √ cumulative voting motion 11.00 Proposal on the election of independent directors of the 10th Board of Directors (4) independent directors to be elected

11.01 Lou Liguang √ √ 11.02 Zeng Qingsheng √ √ 11.03 Sun Jinyun √ √

11.04 Zhou Ji’en √ √

Note: This shareholders’ meeting will also hear the 2025 independent directors’ performance report.

1. The time and media in which each proposal has been disclosed

The above proposal has been approved by the company at the 23rd meeting of the ninth board of directors held on March 2, 2026.

and the 24th meeting of the ninth board of directors held on March 25, 2026 reviewed and approved the relevant public announcements.

The report was disclosed on the website of the Shanghai Stock Exchange on March 3, 2026 and March 26, 2026. (www.sse.com.cn) and "China Securities News" and "Shanghai Securities News".

Proposal 11 The qualifications and independence of independent director candidates are still subject to approval by the Shanghai Stock Exchange.

If there is no objection to the proposal after review, the shareholders' meeting can vote.

2. Special resolutions: 7

3. Proposals for separate counting of votes for small and medium investors: 3, 4, 5, 6, 7, 9, 10, 11

4. Proposals involving related shareholders’ avoidance of voting: 5, 6, 9

Names of related shareholders who should avoid voting: Shareholders who have an interest in the above-mentioned proposals should avoid voting.

5. Proposals involving preference shareholders’ participation in voting: Not applicable

6. Things to note when voting at the shareholders’ meeting

(1) If the company’s shareholders exercise their voting rights through the online voting system of the Shanghai Stock Exchange’s shareholders’ meeting, they shall You can log in to the trading system voting platform (through the trading terminal of the securities company designated for trading) to vote.

You can also log in to the Internet voting platform (website: vote.sseinfo.com) to vote. first login

To vote on the mainland Internet voting platform, investors need to complete shareholder identity authentication. For specific operations please

See the Internet voting platform website description.

(2) The number of electoral votes cast by shareholders exceeds the number of electoral votes they possess, or the number of votes cast by shareholders in the margin election exceeds the number of electoral votes they have. If the number of candidates exceeds the number of candidates, their votes for the motion will be deemed to be invalid votes.

(3) The same voting right is voted repeatedly through on-site, online voting platform of the Exchange or other methods,

The results of the first vote shall prevail.

(4) For shareholders holding multiple shareholder accounts, the number of voting rights that can be exercised is the total number of shareholder accounts under their names. The total number of common stocks of the same category and preferred stocks of the same variety held.

If shareholders holding multiple shareholder accounts participate in online voting at the shareholders’ meeting through the Exchange’s online voting system,

You can participate through any of its shareholder accounts. After voting, all shareholder accounts are deemed to be in the same category.

Both ordinary shares and preferred shares of the same type have voted with the same opinion.

If a shareholder holding multiple shareholder accounts votes repeatedly through multiple shareholder accounts, all

The voting opinions of the same class of ordinary shares and the same variety of preferred stocks under the shareholder account shall be expressed in the form of each class. The results of the first vote for stocks of various types shall prevail.

(5) Shareholders must vote on all proposals before they can be submitted.

(6) The voting method for electing independent directors using the cumulative voting system, see Appendix 2 for details.

4. Participants at the meeting

(1) Register at the Shanghai Branch of China Securities Depository and Clearing Co., Ltd. at the market close in the afternoon on the equity registration day Registered shareholders of the company have the right to attend the shareholders' meeting (see the table below for details), and may submit in writing

Appoint a proxy to attend meetings and vote. The agent does not have to be a shareholder of the company.

Share class Stock code Stock abbreviation Equity registration date A shares 600276 Hengrui Pharmaceutical 2026/4/8

(2) Directors and senior managers of the company. (3) Lawyers hired by the company.

(4) Other personnel

5. Meeting registration method

Participating shareholders (including shareholder agents) need to provide the following documents when registering or reporting:

1. Legal person shareholders: The legal representative of a legal person shareholder who attends the meeting must hold a business license, personal identity certificate, a valid certificate that can prove that he has the qualifications of a legal representative; if an agent is entrusted to attend the meeting, the agent shall

You should hold a business license, personal ID card, and written authorization issued by the legal representative of the legal person shareholder unit in accordance with the law.

Letter of authorization (see attachment 1 for details).

2. Individual shareholders: Individual shareholders who attend the meeting in person should hold their ID cards or other documents that can identify them.

a valid ID card; if an agent is entrusted to attend the meeting, the agent should also hold the agent’s valid ID card, Shareholder power of attorney (see attachment 1 for details).

3. Margin financing and securities lending investors who attend the meeting should hold the business license and certificate of the securities company related to margin trading and securities lending.

Securities account certificate and the power of attorney issued to the investor; if the investor is an individual, he should also hold his/her personal

ID card or other valid documents that can show their identity. If the investor is a unit, he should also hold the unit's business License, ID card of the participant, and power of attorney issued by the legal representative of the unit (see attachment 1 for details).

(2) Registration time: April 9, 2026, morning: 9:30-11:30, afternoon: 13:00-16:00

(3) Registration location: Jiangsu Hengrui Pharmaceutical Co., Ltd.

(4) Shareholders can register by email or letter (copies of relevant certificates are required),

The email or letter will be subject to receipt by the company within the registration time, and please indicate your contact on the email or letter.

phone. 6. Other matters

(1) Shareholders or agents attending the meeting shall bear their own food, accommodation and transportation expenses.

(2) Contact information

Contact: Capital Markets and Securities Affairs Department

Contact number: 021-61053323 Email: [email protected]

Contact address: No. 1288 Haike Road, Pudong New District, Shanghai

Announcement is hereby made.

Board of Directors of Jiangsu Hengrui Pharmaceutical Co., Ltd.

March 25, 2026

Attachment 1: Power of attorney

Attachment 2: Description of voting methods for electing directors and independent directors using the cumulative voting system

Attachment 1: Power of attorney

Power of attorney

Jiangsu Hengrui Pharmaceutical Co., Ltd.:

Mr. (Ms.) is hereby entrusted to represent this unit (or myself) to attend on April 16, 2026. The company's 2025 Annual Shareholders' Meeting will be held on the same day, and the voting rights will be exercised on behalf of the company.

Number of common shares held by the client:

Number of preferred shares held by the client:

Client shareholder account number:

Serial number Name of non-cumulative voting motion Agree Oppose Abstain 1 The company’s 2025 board of directors work report 2 The company’s 2025 annual report

The company's 2025 profit distribution plan and withdrawal of shares 3 The East Council authorized the board of directors to set an interim dividend for 2026 plan motion 4 Proposal on Re-appointment of Accounting Firm About the Company’s Directors and Senior Management in 2025

Proposal on salary implementation About purchasing directors and senior management liability insurance

motion Regarding the proposal to the shareholders’ meeting to grant the board of directors additional issuance of the company

Proposal for general authorization of shares Proposal on formulating and revising some of the company's governance systems 8.00 case 8.01 Proposal on amending the "Rules of Procedure for Shareholders' Meetings" 8.02 Proposal on amending the "Rules of Procedures of the Board of Directors" Regarding the formulation of the "Remuneration Management for Directors and Senior Management Personnel" 8.03 Proposal on the Management System Discussion on the remuneration plan for directors and senior managers

case Regarding the election of non-independent directors of the tenth board of directors 10.00 motion

10.01 Sun Piaoyang 10.02 Dai Hongbin 10.03 Feng Ji

10.04 Zhang Lianshan 10.05 Jiang Ningjun 10.06 Guo Congzhao

Serial number Cumulative voting proposal name Number of votes 11.00 Proposal on the election of independent directors of the 10th Board of Directors / 11.01 Lou Liguang

11.02 Zeng Qingsheng 11.03 Sun Jinyun 11.04 Zhou Ji'en

Signature (stamped) of the principal: Signature of the trustee:

Trustee’s ID number: Trustee’s ID number:

Commission date: year month day

Remarks:

The client should choose one of the "agree", "objection" or "abstain" intentions in the power of attorney and check "√". If the principal does not give specific instructions in this power of attorney, the trustee has the right to make instructions according to his own wishes.

Decide.

Appendix 2: Description of voting methods for electing directors and independent directors using the cumulative voting system

1. The election of candidates for directors of the shareholders’ meeting and the election of independent director candidates are numbered as separate proposal groups.

Investors should vote for each candidate under each proposal group.

2. The number of declared shares represents the number of electoral votes. For each proposal group, each shareholder owns one share of the proposal group.

The total number of votes for an equal number of directors to be elected under the proposal group. If a shareholder holds 100 shares of a listed company, the

There are 10 directors to be elected at the second shareholders' meeting, and there are 12 director candidates. Then the shareholder will vote for the board of directors election proposal group. Has 1,000 shares of electoral votes.

3. Shareholders shall vote within the limit of the number of electoral votes for each proposal group. Shareholders according to their own wishes

When voting, you can either concentrate your electoral votes on a certain candidate or you can vote on different candidates in any combination.

same candidates. After the voting ends, the votes for each motion will be cumulatively calculated.

4. Example: A listed company convened a shareholders' meeting to re-elect the board of directors using a cumulative voting system. Five directors should be elected.

There are 6 director candidates; 2 independent directors should be elected, and there are 3 independent director candidates. subject to voting

The matters are as follows: cumulative voting motion

4.00 Proposal on election of directors Number of votes cast 4.01 Example: Chen×× 4.02 Example: Zhao ××

4.03 Example: Jiang ×× … … 4.06 Example: Song ×× 5.00 Proposal on the election of independent directors Number of votes cast

5.01 Example: Zhang ×× 5.02 Example: Wang×× 5.03 Example: Yang ××

An investor holds 100 shares of the company at the close of the equity registration date and uses a cumulative voting system.

(She) has 500 votes on motion 4.00 "On the election of directors", and 500 votes on motion 5.00

The "Proposal on the Election of Independent Directors" has 200 votes.

The investor can vote as he or she wishes on Proposal 4.00, subject to a limit of 500 votes. He (she) is both

The 500 votes can be concentrated on a certain candidate, or distributed to any candidate in any combination.

As shown in the table: Number of votes cast Serial number Bill name Method 1 Method 2 Method 3 Method… 4.00 Proposal on the election of directors - - - - 4.01 Example: Chen×× 500 100 100 4.02 Example: Zhao×× 0 100 50 4.03 Example: Jiang ×× 0 100 200

… … … … … … 4.06 Example: Song ×× 0 100 50