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Asymchem Laboratories (Tianjin) Co., Ltd. Asymchem Pharmaceutical Group (Tianjin) Co., Ltd.

(a joint stock limited company incorporated in the People's Republic of China) (Stock code: 6821)

Overseas regulatory announcement

This overseas regulatory announcement is made by the Company in accordance with Rule 13.10B of the Rules Governing the Listing of Securities on The Stock Exchange of Hong Kong Limited.

The full Chinese text of the following information published by the Company on the Shenzhen Stock Exchange website is hereby provided for reference only.

By order of the board of directors

Asymchem Pharmaceutical Group (Tianjin) Co., Ltd. Dr. Hao Hong Chairman, Executive Director and Chief Executive Officer

Tianjin, China, June 17, 2026

As of the date of this announcement, the Company’s Board of Directors consists of Dr. Hao Hong, Chairman and Executive Director, and Ms. Yang Rui, Executive Director.

, Mr. Zhang Da and Mr. Hong Liang, non-executive directors Dr. Ye Song and Ms. Zhang Ting, and independent non-executive director Sun Composed of Dr. Xuejiao, Dr. Hou Xinyi and Mr. Xie Weikai.

Asymchem Pharmaceutical Group (Tianjin) Co., Ltd.

Derivatives investment management system

(Revised in year and month) 2026 6

Asymchem Pharmaceutical Group (Tianjin) Co., Ltd.

Derivatives investment management system

Chapter 1 General Provisions

Article 1 In order to regulate Asymchem Pharmaceutical Group (Tianjin) Co., Ltd. and its subsidiaries (hereinafter referred to as

(hereinafter referred to as the "Company" or "Subsidiary") derivatives trading activities, control derivatives trading risks, in accordance with the "China

Securities Law of the People's Republic of China, Accounting Law of the People's Republic of China, and Stock Listing Rules of the Shenzhen Stock Exchange

"Shenzhen Stock Exchange Self-Regulatory Supervision Guidelines for Listed Companies No. 7 - Transactions and Related Transactions" and other laws and regulations

This system is specially formulated in accordance with the relevant provisions of political laws, regulations and the Articles of Association, and in combination with the company's actual business conditions.

Article 2 Derivatives as mentioned in this system refer to those traded on and off-exchange, or non-traded, and are essentially futures,

Options, forwards, swaps, non-standardized option contracts and other products or a combination of the above products. The basics of derivatives

Assets may include securities, indices, interest rates, exchange rates, currencies, commodities, other targets, or the above

A combination of underlying assets; either physical delivery or cash difference settlement can be adopted; both margin and margin can be used

Or guarantee or mortgage for leveraged transactions, or unsecured or unsecured credit transactions.

Article 3 This system applies to derivatives transactions of the company and its holding subsidiaries. Without the consent of the company, the company

The company's holding subsidiaries are not allowed to engage in derivatives transactions.

Article 4 The company and its subordinate units shall strictly control the types and scale of derivatives transactions, and

Product transactions include RMB forward foreign exchange settlement and sales, forward foreign exchange sales and swaps (including exchange rate swaps and interest rate swaps),

Currency options and other businesses are the main business, mainly for the purpose of hedging.

Article 5 Regarding information related to carrying out derivatives business, the company shall follow the relevant information issued by the securities regulatory authorities.

Relevant regulations shall be disclosed in interim reports or periodic reports.

Chapter 2 Risk Control of Derivatives Trading

Article 6 Before a company carries out derivatives business, the company’s financial center or a consulting agency shall be responsible for the assessment.

Business risks of derivatives, analyze the feasibility and necessity of the business, and assess changes in emergencies and risks

Report the situation promptly.

Article 7 Before conducting derivatives transactions, a company shall formulate corresponding accounting policies and determine the

Measurement and accounting methods for transaction business.

Article 8 The company’s audit department is responsible for random inspections of derivatives trading business, supervising the compliance of transaction processes,

Risk management and control are in place.

Article 9 Before conducting derivatives transactions, a company should establish a derivatives trading working group. The trading group should

Equipped with professionals such as trading decision-making, business operations, and risk control. Personnel involved in transactions should fully understand derivatives

Risks in derivatives trading, strict implementation of business operations and risk management systems for derivatives trading.

Article 10 The company’s board of directors shall review and approve derivatives transactions within its external investment authority stipulated in the Articles of Association.

matters. Derivative investment matters that exceed the prescribed authority shall be submitted to the shareholders' meeting for review. Company management is empowering

Responsible for business operations such as the specific amount and time of derivatives transactions within the scope.

Article 11 Before conducting derivatives business, a company shall conduct transactions between multiple markets and multiple products.

Compare and inquire; if necessary, you can hire a professional institution to analyze and compare the derivatives to be selected.

Article 12 The company shall conduct derivative transactions in accordance with the Accounting Standards for Business Enterprises No. 22 - Recognition and Measurement of Financial Instruments.

The fair value of the product transaction is determined, and the derivatives are determined in accordance with the "Accounting Standards for Business Enterprises No. 37 - Presentation of Financial Instruments"

Products are listed and disclosed.

Article 13 The company shall strictly control the type and scale of derivatives business and shall not exceed the actual needs of the business.

When engaging in complex derivatives transactions, you cannot engage in derivatives speculation under the pretext of hedging.

Chapter 3 Review Procedure for Derivatives Business

Article 14 All derivatives transactions of the company must be submitted to the board of directors for review and constitute derivatives of related transactions.

For product transactions, voting procedures for related-party transactions must be implemented.

When a company engages in derivatives trading, it shall prepare a feasibility analysis report and submit it to the board of directors for review.

Article 15 If a derivatives transaction falls under any of the following circumstances, it shall be submitted to the stock exchange after deliberation and approval by the board of directors.

Eastern Conference review:

(1) The upper limit of the trading margin and premium expected to be used (including the price of the security provided for the transaction)

value, the estimated credit limit of financial institutions, the deposit reserved for emergency measures, etc., the same below) accounting for public

More than 50% of the company's latest audited net profit, and the absolute amount exceeds RMB 5 million;

(2) The highest contract value expected to be held on any trading day accounts for 10% of the company’s latest audited net assets

More than 50%, and the absolute amount exceeds RMB 50 million;

(3) The company engages in derivatives transactions not for the purpose of hedging.

Due to reasons such as transaction frequency and timeliness requirements, it is difficult for the company to perform review procedures and review procedures for each derivatives transaction.

If there is a disclosure obligation, the scope, amount and duration of derivatives transactions in the next twelve months can be reasonably assessed.

Anticipate and review. The usage period of the relevant quota should not exceed twelve months, and the amount at any point in time during the period (including

The relevant amount of re-trading the proceeds from the aforementioned transactions) shall not exceed the amount that has been reviewed.

Article 16 The company shall establish a strict job responsibility system for derivatives trading business and clarify the relevant business

The responsibilities, authorities, decision-making, execution, and fund management of business departments and positions are separated, restricted, and supervised from each other.

The audit committee of the company's board of directors reviews the necessity, feasibility and risk control of derivatives transactions,

When necessary, professional institutions can be hired to issue feasibility analysis reports; strengthen the risk management of futures and derivatives transactions.

Evaluate and supervise risk control policies and procedures, promptly identify relevant internal control deficiencies and take remedial measures.

Chapter 4 Subsequent Management of Derivatives Business

Article 17 The company’s derivatives trading business working group shall track the open market price or fair price of derivatives.

value changes, promptly assess the risk changes of the derivatives business that has been carried out, and report to the review team at the end of each quarter

Report from the Planning Department.

When the impairment of the fair value of a company's traded derivatives is equal to the change in the value of assets (if any) used to hedge risks,

The total amount is automatically added up, resulting in a total loss or floating loss amount that is attributable to the listed company in the latest audited period of the company.

When the net profit of shareholders of the company exceeds 10% and the absolute amount exceeds RMB 10 million, the board of directors shall make a temporary announcement and

disclosed at the time.

Article 18 For derivatives transactions that do not fall under centralized settlement and clearing on the exchange, the company’s derivatives

The transaction working group should pay close attention to the changes in counterparty credit risk and conduct regular review of the credit risk of the counterparty.

Track and evaluate the status and performance capabilities of the counterparty, and adjust the counterparty's performance collateral position accordingly.

Article 19 The company’s derivatives trading working group shall, based on the characteristics of the traded derivatives,

Set appropriate stop loss limits for derivatives or different counterparties, clarify the stop loss processing business process, and strictly implement it.

Implement stop loss regulations.

Article 20 The company’s derivatives trading working group shall promptly submit risk reports to the company’s management and board of directors.

Analysis report. The content should include the execution status of derivatives trading authorization, derivatives trading positions, risk assessment

Estimate results, profit and loss status of derivatives transactions in the current period, implementation of stop loss limits, etc.

Article 21 Companies should formulate practical emergency measures based on the characteristics of the derivatives business they have carried out.

Prepare handling plans to promptly respond to major emergencies that may occur during derivatives business operations.

Article 22 The company shall disclose relevant information on derivatives transactions that have been carried out in regular reports.

Disclosure, the disclosure includes:

1. Positions of derivatives transactions at the end of the reporting period. Derivatives holdings that have not expired at the end of the period should be disclosed in a classified manner.

The number of positions, contract amount, maturity period, and proportion to the company’s net assets at the end of the reporting period, etc.; and explain the methods adopted.

Classification methods and standards used.

2. Changes in floating profits and losses of the combination of traded derivatives and their risk hedging assets, and their impact on the company

The impact on current profit and loss;

3. Risk analysis and control measures for derivatives positions, including but not limited to market risk, liquidity risk

insurance, credit risk, operational risk, legal risk, etc.;

4. Changes in market prices or product fair values of traded derivatives during the reporting period, for derivatives

The analysis of fair value should disclose the specific methods used and the setting of relevant assumptions and parameters;

5. Whether the company’s accounting policies and specific accounting principles for derivatives have changed compared with the previous reporting period

Description of significant changes;

6. Other contents required to be disclosed by relevant departments.

Chapter 5 Supplementary Provisions

Article 23 This system shall be implemented from the date of approval by the company's board of directors.

Article 24 Matters not covered by this system shall be handled in accordance with relevant national laws, regulations, normative documents and

The relevant provisions of the Articles of Association shall be implemented. This system is consistent with relevant laws, regulations, normative documents and the

If the relevant provisions of the Articles of Association are inconsistent with the relevant laws, regulations, normative documents and the Articles of Association of the Company,

stipulations shall prevail.

Article 25 The right to interpret this system belongs to the company's board of directors.