Silence Therapeutics Announces Leadership Changes

LONDON--(BUSINESS WIRE)--$SLN #SenseofSilence--Silence Therapeutics plc, Nasdaq: SLN (“Silence” or “the Company”), a global clinical-stage company developing novel siRNA (short interfering RNA) therapies, today announced that Craig Tooman, who has served as the Company’s President, Chief Executive Officer and Board member since 2022, agreed by mutual consent to end his employment with the Company effective 14 December 2025.

Iain Ross, Chairman of the Silence Board, will lead the Company with immediate effect on an interim basis. Additionally, James Ede Golightly, a former Silence Non-Executive Director, has been re-appointed to the Company’s Board of Directors. An additional appointment of an US-based Board member is anticipated in due course.

Iain Ross, Chairman of Silence, said: "We thank Craig for his many contributions to Silence and wish him well for the future. The Company is in robust health both financially and operationally, and we look forward to further commercial and scientific advancements with our pipeline.”

About Silence Therapeutics

Silence Therapeutics is a global clinical-stage biotechnology company committed to transforming people’s lives by silencing diseases through precision engineered medicines created with proprietary siRNA (short interfering RNA) technology. Silence leverages its mRNAi GOLD™ platform to create innovative siRNAs designed to precisely target and silence disease-associated genes in the liver, which represents a substantial opportunity. Silence focuses on areas of high unmet medical need with programs advancing in cardiovascular disease, hematology and rare diseases. For more information, please visit https://www.silence-therapeutics.com/.

Contacts

Inquiries:

Silence Therapeutics plc

Gem Hopkins, VP, IR and Corporate Communications Tel: +1 (646) 637-3208 [email protected]