/Jiuqiang Biology: Announcement on the Company Obtaining an Invention Patent Certificate
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Jiuqiang Biology: Announcement on the Company Obtaining an Invention Patent Certificate

Shenzhen Stock Exchange
2025/12/18

Securities code: 300406 Securities abbreviation: Jiuqiang Biotech Announcement number: 2025-119 Bond code: 123150 Bond abbreviation: Jiuqiang Convertible Bonds

Beijing Jiuqiang Biotechnology Co., Ltd.

Announcement on the Company Obtaining an Invention Patent Certificate

The company and all members of the board of directors guarantee that the contents of the announcement are true, accurate and complete, and that there are no false records, misleading statements or major omissions.

Beijing Jiuqiang Biotechnology Co., Ltd. (hereinafter referred to as "Jiuqiang Bio" or the "Company") recently received 3 patent certificates issued by the State Intellectual Property Office of the People's Republic of China. The details are as follows:

1. Basic situation of patents

Serial number Patent number Patent name Patentee Patent type Application date Grant date Certificate number Self-lubricating rotation

Installation and equipment

ZL202510

1 There is a self-lubricating device invented by Jiuqiang Biology 2025.06.17 2025.12.16 No. 8579244 811797.1

of slewing device

Testing equipment

ZL202310 a conjugate

2 Jiuqiang Biology Invention 2019.12.31 2025.12.16 Preparation method of No. 8582941 365160.5

ZL202310 Preparation of conjugates

3 Jiuqiang Biology Invention 2020.01.03 2025.12.16 No. 8583445

810455.9 Preparation method

Note: The term of invention patent rights is twenty years from the date of application.

Summary of invention patent:

  1. The invention relates to a self-lubricating rotary device and a detection instrument equipped with the self-lubricating rotary device. The self-lubricating rotary device includes: an inner ring, which is provided with an accommodating groove that opens radially outward; and an outer ring, which is installed on the periphery of the inner ring and is provided with a boss corresponding to the accommodating groove. The boss is located in the receiving groove; and a plurality of sliding pieces are installed on the boss and located in the receiving groove; wherein the outer ring and the inner ring can rotate relative to each other around a common axis, and the outer ring can drive the plurality of sliding pieces to rotate together relative to the inner ring. The present invention uses the sliding piece to reduce the rotational friction between the inner ring and the outer ring, and no longer needs to rely on lubricating grease, thereby reducing the maintenance workload. In addition, the present invention has a simple structure, low manufacturing cost, and is conducive to the modular design of the equipment.

  2. The present invention relates to a method for preparing a conjugate. Specifically, the glucose-6-phosphate dehydrogenase mutant of the present invention includes one mutation selected from the following: D306C, D375C, and G426C compared to wild-type glucose-6-phosphate dehydrogenase. The detection kit prepared using the glucose-6-phosphate dehydrogenase mutant of the present invention has strong specificity, high sensitivity, easy operation, short detection time, accurate quantification, and is suitable for high-throughput detection.

  3. The present invention relates to a method for preparing conjugates. Specifically, the glucose-6-phosphate dehydrogenase mutant of the present invention includes one mutation selected from the following or a combination thereof compared to wild-type glucose-6-phosphate dehydrogenase: D306C, D375C, G426C. The detection kit prepared using the glucose-6-phosphate dehydrogenase mutant of the present invention has strong specificity, high sensitivity, easy operation, short detection time, accurate quantification, and is suitable for high-throughput detection.

2. Impact on the company

Obtaining the above-mentioned invention patent certificate will not have a significant impact on the company's recent production and operations, but it will help leverage the company's intellectual property advantages, promote technological innovation, enhance the company's core competitiveness, and form a continuous innovation mechanism.

Announcement is hereby made.

Board of Directors of Beijing Jiuqiang Biotechnology Co., Ltd.

December 18, 2025