/Mitochondria-targeted Atovaquone: A More Potent And More Effective Antitumor, Antimicrobial, And Antimalarial Drug
Abstract
The present invention provides novel mitochondria-targeted Atovaquone compounds (Mito-ATO), a mitochondria-targeted derivative of Atovaquone, and methods of using such compounds. Methods of treating cancer using mito-ATO are also provided. Methods of enhancing an anti-tumor immune response by administering mito-ATO are further provided.
Full Text
What is claimed is:
The present invention provides novel mitochondria-targeted Atovaquone compounds (Mito-ATO), a mitochondria-targeted derivative of Atovaquone, and methods of using such compounds. Methods of treating cancer using mito-ATO are also provided. Methods of enhancing an anti-tumor immune response by administering mito-ATO are further provided.
Timeline
Filed
02/19/2026Published
06/25/2026Granted
Not AvailableIPC Codes(7)
A61K 31/66:Phosphorus compounds
A61K 31/122:having the oxygen atom directly attached to a ring, e.g. quinones, vitamin K1, anthralin
A61K 45/06:Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca