An ultrasonic surgical instrument includes an ultrasonic transducer and an ultrasonic waveguide coupled to the ultrasonic transducer and extending therefrom. The ultrasonic waveguide includes a proximal body portion coupled to and extending distally from the ultrasonic transducer and defining a longitudinal axis. The ultrasonic waveguide further includes a distal body portion defining a blade, and a plurality of spheres of material arranged in a series. The plurality of spheres of material extend between and interconnect the proximal body portion and the distal body portion. At least one sphere of material of the plurality of spheres of material is configured to articulate relative to at least one other sphere of material of the plurality of spheres of material to thereby articulate the distal body portion from an aligned orientation on the longitudinal axis to an articulated orientation angled off the longitudinal axis.