Abstract
The present disclosure relates anti-PD-1/anti-VEGF immunocytokines, particularly with IL-2. Also described herein are bispecific anti-PD-1 and anti-VEGF constructs. IL-2 polypeptides are also provided herein. Also provided herein are pharmaceutical compositions and methods of treatment using the aforementioned compositions.
Full Text
What is claimed is:
The present disclosure relates anti-PD-1/anti-VEGF immunocytokines, particularly with IL-2. Also described herein are bispecific anti-PD-1 and anti-VEGF constructs. IL-2 polypeptides are also provided herein. Also provided herein are pharmaceutical compositions and methods of treatment using the aforementioned compositions.
Timeline
Filed
03/17/2026Published
07/02/2026Granted
Not AvailableIPC Codes(5)
C07K 16/28:against receptors, cell surface antigens or cell surface determinants
A61K 39/00:Medicinal preparations containing antigens or antibodies (materials for immunoassay G01N 33/53)
A61P 35/00:Antineoplastic agents