Provided herein are methods for treating or preventing progression of cervical cancer in an individual, including administering to the individual an effective amount of an anti-human epidermal growth factor receptor 2 (HER2) antibody-drug conjugate that comprises an anti-HER2 antibody and a cytotoxic molecule. Also provided herein are methods for treating or preventing progression of cervical cancer in an individual, including administering to the individual an effective amount of an anti-HER2 antibody-drug conjugate that includes an anti-HER2 antibody and a cytotoxic molecule, in combination with an anti-PD-1 antibody. Also provided herein are uses of an anti-HER2 antibody-drug conjugate, or an anti-HER2 antibody drug conjugate in combination with an anti-PD-1 antibody, for manufacture of a medicament for treating or preventing progression of a previously treated cervical cancer in an individual. Also provided herein are pharmaceutical compositions for use in treating a previously treated cervical cancer in an individual.