/Methods For Selecting And Treating Patients With Retinal Disease Based On Complement Pathway Hyperactivity
Abstract
Provided herein are methods of treating a subject with a complement pathway inhibitor based on the subject's complement pathway activity. Also provided herein are methods of stratifying a subject into three groups based on the subject's complement pathway activity: hyperactive, homeostatic, and hypoactive, and administering an effective treatment (e.g., complement pathway inhibitors).
Full Text
What is claimed is:
Provided herein are methods of treating a subject with a complement pathway inhibitor based on the subject's complement pathway activity. Also provided herein are methods of stratifying a subject into three groups based on the subject's complement pathway activity: hyperactive, homeostatic, and hypoactive, and administering an effective treatment (e.g., complement pathway inhibitors).
Timeline
Filed
02/27/2026Published
07/02/2026Granted
Not AvailableIPC Codes(7)
G01N 33/564:for pre-existing immune complex or autoimmune disease
A61K 31/454:containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
A61K 31/506:not condensed and containing further heterocyclic rings