The present disclosure provides a touch display panel and a preparation method thereof, and a display apparatus. The touch display panel includes: a first base substrate, including sub-pixel regions; a plurality of light emitting devices, corresponding to the sub-pixel regions one to one; a first pixel defining layer, including first opening regions corresponding to the sub-pixel regions one to one; a plurality of quantum dot layers, in at least part of the first opening regions; a touch module, including a first touch electrode layer; and at least one layer of stacked insulation structure, configured to transmit light emitted by each quantum dot layer and reflect light emitted by the light emitting devices.