Abstract
Methods are disclosed for producing a molecule comprising a polypeptide complex formed by interaction between a first polypeptide comprising a CH3 region comprising a knob modification and a second polypeptide comprising a CH3 region comprising a hole modification.
Full Text
What is claimed is:
Methods are disclosed for producing a molecule comprising a polypeptide complex formed by interaction between a first polypeptide comprising a CH3 region comprising a knob modification and a second polypeptide comprising a CH3 region comprising a hole modification.
Timeline
Filed
03/25/2026Published
07/09/2026Granted
Not AvailableIPC Codes(1)
C07K 16/00:Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies