/Multiplex Genome Editing Of Immune Cells To Enhance Functionality And Resistance To Suppressive Environment
Abstract
Provided herein are methods for producing immune cells with disruption of multiple genes. Further provided are methods for inserting a chimeric antigen receptor at a gene locus of an immune cell.
Full Text
What is claimed is:
Provided herein are methods for producing immune cells with disruption of multiple genes. Further provided are methods for inserting a chimeric antigen receptor at a gene locus of an immune cell.
Timeline
Filed
03/17/2026Published
07/09/2026Granted
Not AvailableIPC Codes(8)
C12N 5/0783:T cells; NK cells; Progenitors of T or NK cells
A61K 40/15:Natural-killer [NK] cells; Natural-killer T [NKT] cells
A61K 40/31:Chimeric antigen receptors [CAR]