/Treatment Of Poor Metabolizers Of Dextromethorphan With A Combination Of Bupropion And Dextromethorphan
Abstract
Disclosed herein is a method of safely treating a nervous system condition with a combination of dextromethorphan and bupropion. This method is intended for patients having a neurological condition or a psychiatric condition, such as major depressive disorder, and a CYP2D6 poor metabolizer genotype or a CYP2D6 poor metabolizer phenotype.
Full Text
What is claimed is:
Disclosed herein is a method of safely treating a nervous system condition with a combination of dextromethorphan and bupropion. This method is intended for patients having a neurological condition or a psychiatric condition, such as major depressive disorder, and a CYP2D6 poor metabolizer genotype or a CYP2D6 poor metabolizer phenotype.
Timeline
Filed
03/19/2026Published
07/23/2026Granted
Not AvailableIPC Codes(3)
A61K 31/137:Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
A61K 9/20:Pills, lozenges or tablets
A61K 31/485:Morphinan derivatives, e.g. morphine, codeine