A clinical decision support system for retinal diseases processes OCT retinal scan images to enhance certain aspects of speckle, which has been found to include relevant information that can be used to enhance the diagnosis and classification of the severity and progression of any disease found in the retina scan image. A copy of the original OCT retinal scan image is processed using a shifted window transformer block to enhance the relevant speckle information, and combine it with the original image, which is then evaluated by a trained system to classify the retinal features, including the speckle.