Abstract
Disclosed are recombinant Cas9 proteins, methods of production, and methods of use for targeted DNA deletions, DNA insertions, or both in a eukaryotic genome. An assay system for evaluating the ability of the recombinant Cas9 proteins for targeted DNA deletions, DNA insertions, or both in a eukaryotic genome is also disclosed.
Full Text
What is claimed is:
Disclosed are recombinant Cas9 proteins, methods of production, and methods of use for targeted DNA deletions, DNA insertions, or both in a eukaryotic genome. An assay system for evaluating the ability of the recombinant Cas9 proteins for targeted DNA deletions, DNA insertions, or both in a eukaryotic genome is also disclosed.
Timeline
Filed
04/13/2026Published
07/30/2026Granted
Not AvailableIPC Codes(4)
C12N 15/90:Stable introduction of foreign DNA into chromosome
C12N 9/16:acting on ester bonds (3.1)
C12N 9/22:Ribonucleases