/Crystalline Forms Of N-(4-(4-(cyclopropylmethyl)piperazine-1-carbonyl)phenyl)quinoline-8-sulfonamide
Abstract

Provided herein are amorphous and crystalline hemisulfate salt forms of the formula. Also provided are pharmaceutical compositions comprising the amorphous and crystalline hemisulfate salt forms, methods for their manufacture, and uses thereof for treating conditions associated with pyruvate kinase such as e.g., pyruvate kinase deficiency.

Full Text

What is claimed is:

Provided herein are amorphous and crystalline hemisulfate salt forms of the formula. Also provided are pharmaceutical compositions comprising the amorphous and crystalline hemisulfate salt forms, methods for their manufacture, and uses thereof for treating conditions associated with pyruvate kinase such as e.g., pyruvate kinase deficiency.
Timeline
Filed
03/26/2026
Published
07/30/2026
Granted
Not Available
IPC Codes(1)
C07D 401/12:linked by a chain containing hetero atoms as chain links