Abstract
The present application relates to a preparation method and application of a chiral amine compound and its salt. The method comprises the following steps: (1) causing compound 1 to react in the presence of imine reductase, NADP, glucose dehydrogenase, glucose, a solvent, and a co-solvent to obtain compound 2 and/or compound 2-A; (2) converting the compound 2 and/or compound 2-A into the chiral amine compound TL-010-2 and its salts.
Full Text
What is claimed is:
The present application relates to a preparation method and application of a chiral amine compound and its salt. The method comprises the following steps: (1) causing compound 1 to react in the presence of imine reductase, NADP, glucose dehydrogenase, glucose, a solvent, and a co-solvent to obtain compound 2 and/or compound 2-A; (2) converting the compound 2 and/or compound 2-A into the chiral amine compound TL-010-2 and its salts.
Timeline
Filed
04/13/2026Published
08/06/2026Granted
Not AvailableIPC Codes(2)
C12P 17/12:containing a six-membered hetero ring
C12P 17/18:containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin