A cardiopulmonary arrest prediction device includes: a right sound detector and a left sound detector configured to detect sounds generated by heartbeat fluctuations at a right Yifeng site and a left Yifeng site and detect sounds generated by respiration fluctuations at the right Yifeng site and the left Yifeng site; a calculation section configured to calculate a stress index of a mammal based on the sounds generated by the heartbeat fluctuations and the sounds generated by the respiration fluctuations and detected by the right sound detector and the left sound detector; a prediction section configured to predict the timing of cardiopulmonary arrest in a mammal based on the stress index calculated by the calculation section; and a notification section configured to notify the timing of cardiopulmonary arrest predicted by the prediction section.