A method for use with tissue of a heart comprises transluminally advancing a frame into the heart while a wire extends alongside an exterior of the frame. Within the heart, the frame is positioned adjacent the tissue such that the wire becomes positioned against the tissue. While the wire remains positioned against the tissue, a tube is transluminally advanced over and along the wire and alongside the frame to the tissue. While the tube remains positioned alongside the frame, an anchor is advanced along the tube to the tissue. the anchor is subsequently anchored into the tissue. Other embodiments are also described.