The present application discloses an intelligent file uploading method, device, and system. The method is applied in a file uploading device, the file uploading device includes a first information processing port and a second information processing port, and includes: the first information processing port determining file descriptor information and target device address information of a file to be uploaded; the second information processing port determining a file content mapping result according to the file descriptor information, performing a block reading and writing operation on the file content mapping result to a data cache area, and performing a data reading and uploading operation on block data in the data cache area according to the target device address information, to obtain a file upload result.