/Compositions And Methods For Characterizing Hepatocyte Stress
Abstract

The disclosure provides compositions and methods for identifying subjects having hepatocyte stress associated with a risk for developing hepatocellular carcinoma (HCC), and therapeutic methods for reducing a subject's risk of HCC, for example, by inhibiting RELB, SOX4, or HMGCS2.

Full Text

What is claimed is:

The disclosure provides compositions and methods for identifying subjects having hepatocyte stress associated with a risk for developing hepatocellular carcinoma (HCC), and therapeutic methods for reducing a subject's risk of HCC, for example, by inhibiting RELB, SOX4, or HMGCS2.
Timeline
Filed
05/07/2026
Published
09/03/2026
Granted
Not Available
IPC Codes(4)
C12Q 1/6886:for cancer (immunoassay for cancer G01N 33/575)
C12Q 1/6883:for diseases caused by alterations of genetic material
G01N 33/57525:of the liver or pancreas