The present invention relates to a chimeric antigen receptor targeting BCMA and uses thereof, and more particularly, to an antibody targeting BCMA, a chimeric antigen receptor comprising the antibody, and CAR-T cells expressing the chimeric antigen receptor. It was confirmed that the chimeric antigen receptor and the CAR-T cell targeting BCMA prepared in the present invention specifically bound to the antigen (BCMA), and activation of the BCMA-bound CAR-T cells was made. In addition, since it was confirmed that the CAR-T cell of the present invention effectively killed BCMA-expressing cells, the chimeric antigen receptor and the CAR-T cell targeting BCMA of the present invention can be applied for use in preventing or treating diseases related to B cell expression or BCMA expression.