Abstract
Provided is a cerebral microbleed animal model, wherein the cerebral microbleed is induced by a Col4a1-targeting gRNA (guide RNA) packaged in AAV-BR1.
Full Text
What is claimed is:
Provided is a cerebral microbleed animal model, wherein the cerebral microbleed is induced by a Col4a1-targeting gRNA (guide RNA) packaged in AAV-BR1.
Timeline
Filed
05/18/2026Published
09/10/2026Granted
Not AvailableIPC Codes(4)
A01K 67/0276:Knock-out vertebrates
C12N 9/22:Ribonucleases
C12N 15/11:DNA or RNA fragments; Modified forms thereof (DNA or RNA not used in recombinant technology C07H 21/00)