/Spirocyclic Linked Tricyclic Compounds
Abstract

Provided herein are compounds of Formula (I) and pharmaceutical compositions thereof that are useful in the treatment of alpha-1 antitrypsin deficiency. Also provided herein are pharmaceutical compositions and kits comprising compounds of Formula (I), as well as methods of treating alpha-1 antitrypsin deficiency.

Full Text

What is claimed is:

Provided herein are compounds of Formula (I) and pharmaceutical compositions thereof that are useful in the treatment of alpha-1 antitrypsin deficiency. Also provided herein are pharmaceutical compositions and kits comprising compounds of Formula (I), as well as methods of treating alpha-1 antitrypsin deficiency.
Timeline
Filed
05/15/2026
Published
09/10/2026
Granted
Not Available
IPC Codes(8)
C07D 491/20:Spiro-condensed systems
A61K 31/438:the ring being spiro-condensed with carbocyclic or heterocyclic ring systems
A61K 31/4747:spiro-condensed