Abstract
The present disclosure provides methods for re-stimulating TIL populations that lead to improved phenotype and increased metabolic health of the TILs and provides methods of assaying for TIL populations to determine suitability for more efficacious infusion after re-stimulation.
Full Text
What is claimed is:
The present disclosure provides methods for re-stimulating TIL populations that lead to improved phenotype and increased metabolic health of the TILs and provides methods of assaying for TIL populations to determine suitability for more efficacious infusion after re-stimulation.
Timeline
Filed
05/27/2026Published
09/17/2026Granted
Not AvailableIPC Codes(9)
C12N 5/0783:T cells; NK cells; Progenitors of T or NK cells
A01N 1/162:Temperature processes, e.g. following predefined temperature changes over time
A61K 40/11:T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells