/Polynucleotide Conjugates Comprising Pln-targeting Polynucleotides And Anti-transferrin Receptor Antibodies And Method Of Use Thereof To Treat Pln-associated Cardiomyopathies
Abstract
Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods of use for antibody-PLN targeting oligonucleotide conjugates (AOC).
Full Text
What is claimed is:
Disclosed herein are polynucleic acid molecules, pharmaceutical compositions, and methods of use for antibody-PLN targeting oligonucleotide conjugates (AOC).
Timeline
Filed
05/22/2026Published
09/17/2026Granted
Not AvailableIPC Codes(4)
A61K 47/54:the modifying agent being an organic compound
A61K 47/68:the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
A61P 9/00:Drugs for disorders of the cardiovascular system