How does the position of donor insert (at 20, 50, or 100 bp from the DSB on PAM-distal or PAM-proximal sides)

/How does the position of donor insert (at 20, 50, or 100 bp from the DSB on PAM-distal or PAM-proximal sides) affect HDR efficiency by influencing resected chromosomal strand-donor homology arm pairing fidelity?

Research Question

How does the position of donor insert (at 20, 50, or 100 bp from the DSB on PAM-distal or PAM-proximal sides) affect HDR efficiency by influencing resected chromosomal strand-donor homology arm pairing fidelity?

2026