/Clinical data concerning the presence/absence of parent-reported wheezing and eczema by two years of age were collected for the enrolled infants. We sought to identify clinical factors and faecal bacterial signatures present both at six weeks and two years of life that were associated with the development of these two conditions. Univariate logistic regression models with a dependent variable of either wheeze (yes/no) or eczema (yes/no) were created for each set of bacterial signatures (OTUs and phyla) and clinical factors (as documented in Table 1; Birth demographics, Two year demographics and number of antibiotics courses by six months of age). Premature infants are known to have a lower incidence of eczema than term infants, hence gestation was included as a confounding factor in all univariate models.