Addition of U46619 (a TXA₂ analog) increases ABCC4 ATPase activity 4-fold compared to the apo-form. U46619 has

/Addition of U46619 (a TXA₂ analog) increases ABCC4 ATPase activity 4-fold compared to the apo-form. U46619 has an EC₅₀ of ~6.4 μM and Vmax of ~83.1 mol Pi min⁻¹ mol⁻¹ protein (Fig. 1b).