/The normalized immunofluorescence intensity in midgut cells infected by the African ZIKV strain was significantly higher than that in cells infected by the Asian ZIKV strain (mean normalized signals of 1.36 ±0.50 and 0.80±0.33, respectively, p<0.0001). The stronger immunofluorescence staining in infected cells suggests that at 1 dpibm, a larger amount of ZIKV E proteins were produced in cells infected with the African strain compared to those infected with the Asian strain.